Yes, you can zone your system electronically, by having a separate thermostat timer for each zone.
This means you can set up different automated running times and temperatures for each zone.
We have, however, found that when clients choose to zone their systems, they usually run almost all of them on the same schedule – negating the need for the additional controls (and money spent).
We would recommend only zoning large areas, not individual rooms – for example, in a two-level home, have each level as one zone.
For very large single level homes, perhaps split the house into two zones.
For rooms that are seldomly used (e.g. guest rooms), the area can manually be turned off at the heating manifold (similar to turning off a tap).